How to Use mRNA technology against pollen allergy

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With mRNA technology against pollen allergy

With the rising temperatures, the flowering period slowly begins. But not everyone is happy about that because allergy sufferers often must fight hard. Hazel and alder are the main problems at the moment. In the future, however, mRNA technology could help here.

Nature WEATHER awakens, but so do numerous allergies. Many are familiar with the problems: the nose is running; the eyes are watering, and the throat is sore. Shortly, however, this could be avoidable – with the help of mRNA technology.

When it comes to fighting allergies, it has a significant advantage over conventional desensitization, in which the body is supposed to get used to the allergy substances, says environmental doctor Hans-Peter Hutter: “The advantage of this option is that you don’t bring the antigen directly into the body, but the blueprint. This messenger RNA is nothing more than a copy of the allergen, a copy of its key characteristics.”

Medication, desensitization, and allergen avoidance

In the case of an allergy, the body overreacts to one or more proteins. If the mRNA technology to combat allergies comes onto the market, you can create an exact profile of the allergy sufferer beforehand, Hutter explains to noe.ORF.at. In this way, one can find out which proteins are causing the problems, produce them artificially and inject them into the body, for example through a syringe or the nasal mucosa.

“The messenger substance migrates into the cell, and that is where the copying process begins,” explains Hutter. “Ultimately, these proteins, namely the antigen to which you are allergic, are produced – you can say about an endogenous production site.”

Hutter in conversation with one.ORF.at

However, given the ongoing pandemic, it may be some time before the method comes onto the market. However, there is great hope for the treatment of allergies using mRNA technology. Especially about the worsening situation for allergy sufferers, because: “We know that the pollen season now begins in January or February and ends in November,” says Hutter. The climate crisis is to blame.

Until then, the environmental physician advises those affected to take a combination of drug treatment, conventional desensitization, and avoidance of allergens – “that you say goodbye in good Viennese”. In addition, ventilation systems that filter out pollen could help at home. And you can also take precautions when planning your vacation, according to the expert. So, you should go on holiday when it is pollen season at home or head for travel destinations where there is less

 

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